All required qualifications must be documented on application materials.

Required Qualifications:

• Candidates must have received their PhD degrees in cell biology or related field and should have experience in cancer biology.
• Experience in cell culture and mouse models
• Excellent verbal and written skills are required
• Track record of scientific publications

Preferred Qualifications:

• Experience with flow cytometry
• Experience with immunofluorescence of cells and/or tissues, and imaging
• Experience with basic molecular and cellular biology techniques including: nucleic acid preparation (DNA/RNA), PCR, qRT-PCR, Western blotting, immunohistochemistry

Job description:

A breast cancer research lab is seeking a post-doctoral associate to join the laboratory focused on basic and translational breast cancer research. We use cell culture and animal models to examine molecular mechanisms regulating the development and progression of breast cancer with a specific focus on the tumor microenvironment. Candidates will be expected to independently design experimental protocols, and carryout experiments and interpret the results. Candidates will be expected to be coauthor and submit manuscripts and research grants as well as train and supervise graduate and undergraduate students and/or research technicians.

Responsibilities

• Independently create and plan experiments based on knowledge of the field, gained by researching the relevant literature, contacting other researchers in the field and collaboration with other labs
• Perform experiments using methods created according to previously published methods or novel methods developed as needed
• Analyze data collected from experiments, generate manuscript figures, write and edit manuscripts.
• Review literature relating to research projects; assist in writing primary research articles, review articles, and grant proposals
• Work collaboratively with others in the lab, train incoming new lab personnel in relevant experimental techniques

50% Conduct investigations or experiments in an assigned area to aid in the solution of a research problem

• Maintain cell culture stocks
• Examine the effects of various drugs or genetic modifications on cell culture growth, survival, migration and invasion in vitro and tumor growth in vivo
• Perform DNA, RNA and protein analysis using PCR, RT-PCR, sequencing, immunoblot analysis, immunofluorescence/immunohistochemistry and flow cytometry

15% Actively participate in research efforts by exploring new possible approaches to problems or suggesting new interpretation of data

• Review literature for alternative technical approaches and implement them in the lab
• Contribute to discussions in weekly lab meetings regarding troubleshooting and implementation of new protocols related to projects being performed by others in the lab

15% Assist in modifying existing techniques and procedures or in developing new ones.

• Analyze the data gathered from the experiments and troubleshoot each specific procedure as required
• Assist and train other members of the laboratory, including undergraduate and graduate students, in proper experimental technique and in following protocols

15% Select and review literature relating to the assigned area. Assist in writing of technical reports and articles for publications. Discuss possible approaches to problems with supervisor

• Discuss possible troubleshooting techniques based on literature review or meetings with other colleagues
• Contribute to manuscript preparation by writing up experimental results and determining how they will contribute to the overall study
• Review literature to incorporate into the manuscripts as background or discussion

5% Manage inventory of lab supplies

• Maintain inventory of lab supplies, tissue culture supplies and stock chemicals
• Maintain lab stocks of solutions and other general reagents

The University of Minnesota offers a comprehensive benefits package including:

·         Competitive wages, paid holidays, vacation and sick leave

·         Low cost medical, dental, and pharmacy plans

·         Health care and dependent daycare flexible spending accounts

·         Wellbeing program with reduced insurance premiums

·         Tuition reimbursement opportunities covering 75%-100% of eligible tuition

·         Student loan forgiveness opportunity

·         Opportunities for growth and promotion

·         Employee Assistance Program

About University of Minnesota Twin Cities

The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.

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