There is an immediate opening for a postdoctoral Research Fellow or Research Associate position in the Division of Clinical Pharmacology at Cincinnati Children's Hospital Medical Center. The position is funded for 5 years. The research is focused on pharmacokinetic/pharmacodynamic modeling and simulation of beta-lactam antibiotics in critically ill children and adults to build evidence for model-informed precision dosing and to translate this work to the bedside in patients. The ideal candidate should have a strong interest in model-informed precision dosing (MIPD), pharmacometrics and biostatistical approaches (such as nonlinear mixed effects modeling and Bayesian statistics) to evaluate and optimize pharmacotherapy.
Cincinnati Children's Research and Training at a Glance:
Among the top in NIH funding for pediatric research institutions
Over 1.4 million square feet of research laboratory space
900+ scientists conducting basic, translational, and clinical research
Over 2000 publications annually in top-tier journals
Access to Employee Resource Groups and Mentorship programs
Postdocs have gone on to careers in academia, biotech, pharma, teaching etc.
-Conduct Research Design, execute, and record analysis and experiments; develop and apply standard scientific protocols to research, and improve current methods and evaluate innovative techniques. Develop and implement human subject research protocols, and design experimental procedures and documentation in accordance with the relevant laws and regulations. Prepare, clean and analyze data. Maintain optimal protocol and accuracy by conducting regular quality and reproducibility checks.
-Dissemination of research Draft, write and edit scientific reports, papers, journal articles and abstracts. Present at local, national and international scientific meetings.
Train and supervise the work of trainees in the program, as appropriate. Maintain an integral role in the group meetings, presentations and publications. Present information on research to others at group meetings, journal clubs and seminars. Demonstrate attendance and punctuality, ability to work independently & display initiative and dedication
May act as a mentor to more junior staff, serve as the contact for resolution of complex issues, provide education, guidance and work direction. May provide input and feedback to managers on hiring decisions, professional development and performance management.
Assist in preparing, writing and maintaining fiscal budget. Monitor expenditures and prepare capital expenditure requests. Prepare, approve and initiate check requests; track funding, maintain accurate balance and resolve any discrepancies.
PhD, PharmD, MD or MS in Pharmacokinetics, Pharmaceutical sciences, Pharmacy, Biostatistics or related discipline at the time of appointment
PhD, PharmD, MD or MS in Pharmacokinetics, Pharmaceutical sciences, Pharmacy, Biostatistics or related discipline at the time of appointment.
Experience with PK/PD modeling and simulation and related software packages
Experience with biostatistics and related programming software
Excellent communication skills and ability to work in a multi-disciplinary team to learn and integrate knowledge across different disciplines
Excitement to learn new skills in pharmacometrics, including population PK modeling, PK/PD modeling and PBPK modeling
Evidenced by first-author published manuscripts
Programming - Basic
Working knowledge of computer programming languages, such as R
Strong organizational and project management to handle projects independently
Ability to prioritize multiple tasks and manage time appropriately to meet deadlines
Strong analytical skills with the ability to make appropriate conclusions based on statistical analysis
Statistics - Basic to Intermediate
Familiarity with statistical software, statistical techniques, statistical process control principles, and graphical data display
Research Methods Skills
Designing and conducting effective research studies that address measurement, data collection, and validity issues; identifying or developing appropriate, accurate, relevant and reliable measurement methods; drawing appropriate conclusions from study results
Communication - Advanced
Excellent verbal, written and interpersonal communication skills with ability with multidisciplinary team members
At Cincinnati Children’s, we come to work with one goal: to make children’s health better. We believe in a team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better, and find energy and inspiration in our shared purpose. If you want to be the best you can be, you can do it at Cincinnati Children’s.