The Advanced Research and Diagnostic Laboratory (ARDL) is a highly complex research laboratory that specializes in support of large multicenter clinical trials and epidemiological studies. Specific areas of interest for faculty at ARDL include identification of novel biomarkers of healthy aging and biomarkers for early detection and monitoring or of patients with diabetes, renal disease, Alzheimer’s disease related dementias and cardiovascular disease. Laboratory support for these multi-center studies ranges from novel biomarker development, implementation of standardized biomarker measurement, and coordinating biospecimen collection and processing. ARDL maintains a large central biorepository of 3-4 million aliquots that supports ongoing biomarker development in all these studies. A unique aspect of the ARDL is that it is a research laboratory that is fully accredited by CLIA/CAP and part of the University of Minnesota Laboratory Medicine and Pathology Department under the Medical School. ARDL supports a wide variety of biomarker platforms spanning the range from genomics, transcriptomics, proteomics to functional approaches. ARDL also utilizes mass spectrometry for accurate quantitation of molecules and targeted multiplexed assays using this platform. Genomics technologies used include a variety of DNA/RNA extraction platforms, quantitative real time PCR, targeted genotyping and next generation sequencing. ARDL performs a wide range of immunoassays ranging from standard ELISAs to targeted multiplexed immunoassays on the Ella platform. ARDL also utilizes proteomic discovery platforms such as Olink and performs ultra-sensitive protein quantitation on the Quanterix platform. In addition, ARDL also performs multi-parameter flow cytometry and has a well established cell culture facility that specializes in cell cryopreservation, EBV based cell transformation, culture of iPSCs and actively developing cell differentiation protocols.
Shift: Tuesday - Friday evenings, Saturday days
Perform laboratory testing on blood, urine and other body fluids according to written procedures. Receives, test request and processes specimens.
Evaluate test results for accuracy and takes appropriate action.
Perform quality control, calibration and maintenance procedures on equipment and analyzers and documents actions appropriately.
Exercise critical thinking to recognize problems and resolve appropriately.
Order, receive and maintain supplies and inventory.
Follow established biological, chemical and physical safety procedures.
Comply with laboratory quality assurance programs and regulatory agency requirements.
The University of Minnesota offers a comprehensive benefits package including:
· Competitive wages, paid holidays, vacation and sick leave
· Low cost medical, dental, and pharmacy plans
· Health care and dependent daycare flexible spending accounts
· Excellent retirement plans with employer match
· Disability and employer paid life insurance
· Wellbeing program with reduced insurance premiums
· Tuition reimbursement opportunities covering 75%-100% of eligible tuition
The University of Minnesota, founded in the belief that all people are enriched by understanding, is dedicated to the advancement of learning and the search for truth; to the sharing of this knowledge through education for a diverse community; and to the application of this knowledge to benefit the people of the state, the nation, and the world.