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Research Specialist
The University of North Carolina at Chapel Hill
Employment Type: Permanent Staff (SHRA) Vacancy ID: P012343 Salary Range: $48,154- $56,000 Position Summary/Description: The Heinzen Lab in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC-Chapel Hill Eshelman School of Pharmacy focuses on studying the genetic and genomic basis of epilepsy disorders, including analyses of the role of germline and somatic mutations, and how the regulation of the cellular transcriptome influences the risk and presentation of seizures. The lab uses human induced pluripotent stem cell derived neuronal models' systems to determine how the epilepsy causing genetic variants contribute to disease pathophysiology and to explore novel approaches to drug therapy. We are seeking a full-time Research Specialist to facilitate and help lead research efforts in the lab. Specifically, the Research Specialist will participate extensively in the experiment design, data collection, analysis, and interpretation. The role will be involved with protocol modifications and evaluation of the research study, as well as the study outcome literature and presentation. It serves as the secondary research contact behind the PI. The incumbent will participate with training and handle lab management. The job will be responsible for maintaining cell lines and performing experiments in human induced pluripotent derived neurons and human brain tissue specimens. Experimental procedures will include DNA and RNA extractions, PCR and rtPCR, cell based assays, cyrosectioning, cloning, FAC sorting, immunohistochemistry, imaging, and single cell RNA sequencing. Education and Experience: Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions. Essential Skills: Must be able to read and understand the scientific literature and execute experiments as outlined in laboratory protocols. A high level of responsibility, motivation, attention to detail, independence, and good written and verbal communication skills are required. Proficiency with Microsoft Office (PowerPoint, Excel, Word) and strong math skills are required. Preferred : Bachelor's degree (B.S. or B.A.) in Chemistry, Biology, Biochemistry, Pharmacology, Genetics, Neuroscience, or related discipline with 2-3 years of previous research experience in a biomedical or biological sciences laboratory required. Research experience with human induced pluripotent stem cell models preferred but not required. AA/EEO Statement: The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
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