The Heinzen Lab in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC-Chapel Hill Eshelman School of Pharmacy focuses on studying the genetic and genomic basis of epilepsy disorders, including analyses of the role of germline and somatic mutations, and how the regulation of the cellular transcriptome influences the risk and presentation of seizures. The lab uses human induced pluripotent stem cell derived neuronal models' systems to determine how the epilepsy causing genetic variants contribute to disease pathophysiology and to explore novel approaches to drug therapy.
We are seeking a full-time Research Specialist to facilitate and help lead research efforts in the lab. Specifically, the Research Specialist will participate extensively in the experiment design, data collection, analysis, and interpretation. The role will be involved with protocol modifications and evaluation of the research study, as well as the study outcome literature and presentation. It serves as the secondary research contact behind the PI. The incumbent will participate with training and handle lab management. The job will be responsible for maintaining cell lines and performing experiments in human induced pluripotent derived neurons and human brain tissue specimens. Experimental procedures will include DNA and RNA extractions, PCR and rtPCR, cell based assays, cyrosectioning, cloning, FAC sorting, immunohistochemistry, imaging, and single cell RNA sequencing.
Education and Experience:
Bachelor’s degree in a discipline related to the area of assignment; or equivalent combination of training and experience. All degrees must be received from appropriately accredited institutions.
Must be able to read and understand the scientific literature and execute experiments as outlined in laboratory protocols. A high level of responsibility, motivation, attention to detail, independence, and good written and verbal communication skills are required. Proficiency with Microsoft Office (PowerPoint, Excel, Word) and strong math skills are required.
Bachelor's degree (B.S. or B.A.) in Chemistry, Biology, Biochemistry, Pharmacology, Genetics, Neuroscience, or related discipline with 2-3 years of previous research experience in a biomedical or biological sciences laboratory required. Research experience with human induced pluripotent stem cell models preferred but not required.
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.
Carolina rates among the nation’s great institutions of higher education, set on an historic and beautiful campus that celebrates all four seasons. Carolina’s students, faculty and staff come here from around the world, bringing varied cultural, racial and ethnic heritages that help make UNC-Chapel Hill a thriving intellectual center. We’re repeatedly ranked the nation’s best value in higher education for students seeking to earn a college degree – the University has garnered the top spot each time since the ranking’s launch in 1998.Whether you’ve just started your career, are new to academia or are a seasoned professional with assorted campus experiences to draw on, we hope you will find a great place at Carolina.